AI 🤝 Stem Cells
Apr 25, 2023
Kaley Ubellacker
Market Stirrings 🚩
Here's what the week looked like in pre-seed:
Data aggregated from proprietary research and Crunchbase; valuation estimate based on 10-20% ownership stake.
Good Reads 📖
For the rushed reader …
Our favorite stories in…
For the less rushed reader …

There’s a hot new climate technology in town, and let’s hope it’s at least one brick short of a full load. Heavy industries need to generate heat. Enter heat batteries. One technology implements an insulated steel container to transfer heat through a stack of bricks, where heat can be trapped for days of use.
Last Saturday was Earth Day – or in Nvidia’s case, Earth D(AI)y. Nvidia released an article on how AI is accelerating progress towards climate goals.
Save a tree, and eat an insect. The agriculture sector is responsible for 10% of greenhouse gas emissions. The population is growing, and we need more sustainable sources of protein to accommodate it. Also, alternative protein has a variety of usage cases across pet food, aquafeed, and food for humans.
Duolingo incorporated roleplay. It introduced the “Roleplay” feature as part of a max subscription tier. The feature provides a built-in AI chatbot powered by GPT-4, where users can practice real-world conversations.

Is THE Green Lantern following a green lantern? Ryan Reynolds announced his investment in Nuvei, a global payments technology company.
Samsung Electronics unveiled a new digital health platform for wearable devices. Samsung recognizes smartphones and wearables as the key to revolutionizing healthcare research.

Reach Capital, a leading edtech investor, made firm history with a $215 million raise for its fourth fund. The raise comes during a time where we’ve seen a strong pullback in new edtech deals. Congrats to the team!
techbits
Fire Up the Pre-Seeds🔥
Highlights from this week’s pre-seed raises:
Skarper - Bike better
The Tech: A patented clip-on unit that makes any bike an e-bike
Recently raised: $4.9 million in seed funding from the Starry Group and Mobilitech Capital
Also note: Skarper already has hundreds of distribution requests from around the world and a large waiting list of customers.
Context: The largest lender in Egypt for the unbanked
The tech: An ecommerce ecosystem for consumers, merchants, and enterprises
The raise: $260 million at a $1 billion valuation in early February
Its edge: The only fintech unicorn born in Q1 2023
Clear Street - Save the old stuff for antique shops
The Tech: Modern infrastructure to replace outdated models used in capital markets
Recently Raised: $270 million in Series B funding at a $2 billion valuation
Also Note: Its business model is two-pronged, including charging a fee for transactions as well as financing public market securities. Also, Clear Street has a customer base of 200 institutional sized investors and hundreds of smaller trading entities.
Cortical Labs - Tonight’s special: DishBrain
The Tech: Human stem cells that power AI models
Recently Raised: $10 million led by Horizons Ventures
Also Note: The tech is so powerful because stem cells generalize information better and use less energy. Even Amazon’s CTO Werner Vogels was intrigued after seeing the lab.
Cortica - We should care more about kids
The Tech: Hybrid care programs for children with neurodiverse conditions
Recently Raised: $75 million in post-seed financing
Also Note: Cortica acquired Springtide Child Development, a multisite practice serving children with developmental delays
VintaBio - An overlooked supply chain issue
The Problem: A bottleneck in life-saving therapies
The Tech: Developing and manufacturing viral vectors for use in cell and gene therapies
Recently Raised: $64 million in funding led by Silicon Valley's Decheng Capital
Also Note: VintaBio emerged from stealth with a newly appointed CEO and a custom-built manufacturing facility.
Innovamat - Goodbye times tables
The Problem: Teaching math is hard. Learning math is hard
The Tech: A new math curriculum based on understanding, not rote memorization
Recently Raised: $21 million in Series A funding led by Reach Capital
Also Note: Innovamat’s product is well-received by consumers. Dr. Hollyce Schoepp, K-12 Supervisor in NJ, remarked, “Innovamat has brought the fun of learning math to our students and the joy of teaching math to our teachers. It’s been a win-win.”
Outro🚪
Have any questions, feedback, or comments? Just reply here. We iterate and curate the newsletter according to your interests!
Some last matters of business:
If you’re a technologist (engineer or product manager / designer with a technical background) join us on the NVTC LinkedIn group if you haven’t. We’d love to have you!
Sign up here if you’re interested in co-investing with Necessary.
If you’re a startup founder, we’d love to help where we can! Brex provides full-stack finance solutions for startups. Sign up via Necessary and get bonus points.
Thanks for reading, and see you next week!